首页> 外国专利> Method for detecting active ingredient of plant based on evidence by reverse-directed analysis (Reverse-directed analysis)

Method for detecting active ingredient of plant based on evidence by reverse-directed analysis (Reverse-directed analysis)

机译:基于证据的逆向分析法检测植物有效成分的方法

摘要

Conventional methods in this field identify and screen compounds in laboratories that provide cells and animals, and then move on to clinical trials with candidate compounds. Complicating the problem with these methods is that the active compound may not be present in the original herb and a large number of compounds are associated with the results, resulting in long-term research and high costs. . The present invention has solved the following problems: 1) Candidate compounds are identified from test patients showing favorable and safe results. 2) One or more compounds can be identified. 3) Safe and effective compounds may be metabolites or may not be present in herbs. The method of the present invention utilizes a website to gather clinical information. Candidate compounds can be determined by analyzing a common composition from patients. Data for potential therapeutic compounds can be obtained directly from humans. These findings contribute to time and cost savings in pharmaceutical research and development.
机译:该领域的常规方法在提供细胞和动物的实验室中鉴定和筛选化合物,然后进行候选化合物的临床试验。这些方法使问题复杂化的是,原始草药中可能不存在活性化合物,并且大量的化合物与结果相关联,从而导致了长期研究和高成本。 。本发明解决了以下问题:1)从显示良好和安全结果的测试患者中鉴定候选化合物。 2)可以识别一种或多种化合物。 3)安全有效的化合物可能是代谢产物,也可能不存在于草药中。本发明的方法利用网站来收集临床信息。候选化合物可以通过分析患者的常见成分来确定。潜在治疗性化合物的数据可直接从人类获得。这些发现有助于节省药物研发的时间和成本。

著录项

  • 公开/公告号JP2018508084A

    专利类型

  • 公开/公告日2018-03-22

    原文格式PDF

  • 申请/专利权人 チャン;チェンイ;

    申请/专利号JP20170548209

  • 发明设计人 チャン;チェンイ;

    申请日2016-03-03

  • 分类号G06Q50/22;G16H10;

  • 国家 JP

  • 入库时间 2022-08-21 13:10:29

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