首页> 外国专利> HUMAN INTERLEUKIN-7 ENCODING SYNTHETIC DNA, EXPRESSION VECTOR CONTAINING THIS DNA (VERSIONS), HUMAN INTERLEUKIN-7 PRODUCING STRAIN, AND METHOD FOR HUMAN INTERLEUKIN-7 PRODUCTION

HUMAN INTERLEUKIN-7 ENCODING SYNTHETIC DNA, EXPRESSION VECTOR CONTAINING THIS DNA (VERSIONS), HUMAN INTERLEUKIN-7 PRODUCING STRAIN, AND METHOD FOR HUMAN INTERLEUKIN-7 PRODUCTION

机译：编码合成DNA的人白细胞介素7，包含该DNA的表达载体（版本），人白细胞介素7的生产菌株以及人白细胞介素7的生产方法

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FIELD: biotechnology.;SUBSTANCE: synthetic DNA encoding human IL-7 is obtained, its expression vector containing a strain of Chinese hamster ovary cells - recombinant human Interleukin-7 producer, deposited under number RKKK(P) 770D. Strain provides accumulation of up to 180 mg/l of IL-7 in the culture medium for 15 days in serum-free chemically defined medium. Also, a method for glycosylated human IL-7 purification from the culture medium is provided.;EFFECT: obtaining of a high-purity product with high glycosylation and specific activity.;5 cl, 7 dwg, 2 tbl, 5 ex

机译：领域：生物技术;物质：获得编码人IL-7的合成DNA，其表达载体包含中国仓鼠卵巢细胞株-重组人Interleukin-7生产者，保藏号为RKKK（P）770D。在无血清化学成分确定的培养基中，菌株可在培养基中提供高达180 mg / l的IL-7累积15天。并且，提供了一种从培养基中纯化糖基化的人IL-7的方法。效果：获得具有高糖基化和比活性的高纯度产物; 5 cl，7 dwg，2 tbl，5 ex

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公开/公告号RU2615447C1

专利类型
公开/公告日2017-04-04

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE UNITARNOE PREDPRIYATIE GOSUDARSTVENNYJ NAUCHNO-ISSLEDOVATELSKIJ INSTITUT OSOBO CHISTYKH BIOPREPARATOV FEDERALNOGO MEDIKO-BIOLOGICHESKOGO AGENTSTVA;
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申请/专利号RU20150148904
发明设计人 ISHCHENKO ALEKSANDR MITROFANOVICH;PIGAREVA NATALYA VASILEVNA;SIMBIRTSEV ANDREJ SEMENOVICH;PETROV ALEKSANDR VLADIMIROVICH;PROTASOV EVGENIJ ALEKSANDROVICH;KUDLING TATYANA VIKTOROVNA;
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申请日2015-11-13
分类号C07K14/54;C12N5/10;C12N15/24;C12N15/85;C12P21/02;
国家 RU
入库时间 2022-08-21 13:23:39

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