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DNA Multiple tandem shDNA used for tumor-selective drug delivery and use thereof
DNA Multiple tandem shDNA used for tumor-selective drug delivery and use thereof
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机译：用于肿瘤选择性药物递送的dna多串联shDNA及其用途
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摘要
The present invention relates to an amphipathic nucleic acid molecule in which a hydrophobic substance-DNA conjugate and a target ligand-DNA conjugate form a base pair in a multi-series hairpin DNA polymer, a nucleic acid complex comprising the same and a use thereof as a drug delivery vehicle. The drug delivery system of the present invention can selectively deliver drugs to target cells and target tissues, has no cytotoxicity problem, and can release effective cytosol after drug delivery, and can be widely applied to cancer therapy and cell-based drug screening methods .;
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