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Biomarker for differentiating between active and latent tuberculosis in conjunction with Interferon gamma release assay and its use

机译:结合干扰素γ释放测定法区分活动性肺结核和潜伏性结核的生物标志物及其用途

摘要

The present invention discloses a method for determining active tuberculosis and latent tuberculosis by detecting the concentration of VEGF-A in serum by supplementing an interferon gamma release assay such as IGRA, and a composition used in the method. The composition or method of the present invention can be distinguished between latent tuberculosis and active tuberculosis with high sensitivity and specificity, either alone or in conjunction with conventional culture or QFT-IT tests.
机译:本发明公开了通过补充干扰素γ释放测定法例如IGRA来检测血清中VEGF-A的浓度来确定活动性结核和潜伏性结核的方法,以及用于该方法的组合物。本发明的组合物或方法可以单独地或与常规培养或QFT-IT测试一起以高灵敏度和特异性区分潜伏性结核和活动性结核。

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