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A scaffold with extracellular matrix for bone regeneration

机译:具有细胞外基质的骨再生支架

摘要

A and bdECM (demineralized and decellularized bone extracellular matrix); The invention PCL (polycaprolactone), PLGA (poly (D, L-lactic-co-glycolic acid), and β-TCP (tricalcium phosphate) a first layer comprising and a second layer comprising the second layer surrounding the first layer, to a bone-support and a method for. Extracellular matrix is ​​a bone support for the coating of the invention is the support produced in the shape that exactly matches the affected area of ​​bone damage caused from, via a 3D printer, rapid binding and switching than conventional support and attachment of the surrounding bone tissue cells, the proliferation and differentiation improves bone can expect faster bone regeneration effect. We can also expect a more rapid recovery does require steps such as cell transplantation by transplantation of support in a short time to bone injuries.;
机译:A和bdECM(去矿质和去细胞的骨细胞外基质);本发明的PCL(聚己内酯),PLGA(聚(D,L-乳酸-乙醇酸共聚物)和β-TCP(磷酸三钙))的第一层包括和第二层,所述第二层包含围绕第一层的第二层。骨支持物及其方法。细胞外基质是本发明涂层的骨支持物,其产生的形状与通过3D打印机快速粘合引起的骨损伤的受影响区域完全匹配与传统的支撑和附着方式相比,骨的增殖和分化得到改善,可以期待更快的骨骼再生效果;恢复速度更快,还需要通过在短时间内通过支撑移植来进行细胞移植等步骤骨头受伤。

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