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Streptococcus pneumoniae producing hybrid polyserotype capsular polysaccharide and hybrid polyserotype capsular polysaccharide produced therefrom

机译:产生杂交多血清型荚膜多糖的肺炎链球菌和由其产生的杂交多血清型荚膜多糖

摘要

The present invention relates to a method for the treatment of Streptococcus pneumoniae which produces a hybrid polysaccharide capsular polysaccharide pneumoniae) strain and the wzy 19F of the hybrid is directed to a serotype film polysaccharides, in particular serotype of 19A pneumococcal repeating unit wzy 19A gene and serotype 19F Streptococcus pneumoniae of the polymerase of the repeating unit polymerase produced from the strain Confirmed that the pneumococci produced by the coupling effectively produce 19A and 19F hybrid multi-serum-type membrane polysaccharides, and thus the pneumococci and the hybrid multi-serum-type polysaccharides produced therefrom are useful as vaccines against Streptococcus pneumoniae have.
机译:本发明涉及一种治疗肺炎链球菌的方法,该方法产生了杂种荚膜多糖多糖(I>肺炎)菌株和其 wzy 19F。该杂种针对血清型膜多糖,特别是由菌株产生的重复单元聚合酶的聚合酶的19A肺炎球菌重复单元 wzy 19A基因的血清型和19F肺炎链球菌的血清型。这种结合有效地产生了19A和19F杂合多血清型膜多糖,因此,肺炎球菌和由此产生的杂合多血清型多糖可用作抗肺炎链球菌的疫苗。

著录项

  • 公开/公告号KR101712495B1

    专利类型

  • 公开/公告日2017-03-07

    原文格式PDF

  • 申请/专利权人 이화여자대학교 산학협력단;

    申请/专利号KR20130098778

  • 发明设计人 박인호;김경효;

    申请日2013-08-20

  • 分类号C12N1/20;C07K14/315;C12P19/04;C12R1/46;

  • 国家 KR

  • 入库时间 2022-08-21 13:25:56

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