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PLC1 PLC 1 mutant animal model for testing maternal behavior or paternal attentiveness and screening method for agent for treating or preventing the disorder of maternal behavior or paternal attentiveness using said animal model
PLC1 PLC 1 mutant animal model for testing maternal behavior or paternal attentiveness and screening method for agent for treating or preventing the disorder of maternal behavior or paternal attentiveness using said animal model
The present invention is an animal model system capable of verifying the paternal attentiveness of male mice using female mice knocked out of the phospholipase C? 1 gene as a spouse, Is a remedial system that allows vertebrate mice to demonstrate a compensational sub-behavioral response induced by maternal behavioral disturbances in knock-out female mice. Thus, the genetic animal model of the present invention can be used to artificially manipulate the "bad mother" (neglecting mother) environment necessary for studying the biology of paternal attentiveness in non-biparental species Drug treatment, isolation, etc.).
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