首页> 外国专利> METHOD FOR RATING TENDENCY TOWARDS DIFFERENTIATION AMONG UNDIFFERENTIATED CELLS, SALL3 mRNA AS MARKER FOR RATING TENDENCY TOWARDS DIFFERENTIATION, AND METHOD FOR CONTROLLING DIFFERENTIATION ABILITY OF UNDIFFERENTIATED CELLS

METHOD FOR RATING TENDENCY TOWARDS DIFFERENTIATION AMONG UNDIFFERENTIATED CELLS, SALL3 mRNA AS MARKER FOR RATING TENDENCY TOWARDS DIFFERENTIATION, AND METHOD FOR CONTROLLING DIFFERENTIATION ABILITY OF UNDIFFERENTIATED CELLS

机译：在未分化的细胞中向分化进行评分的方法，SALL3 mRNA作为向分化中的评分对策的标记物和控制未分化细胞的分化能力的方法

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摘要

Provided is an easy and labor-saving method for rating tendencies towards differentiation among undifferentiated cells. The method for rating the tendencies towards differentiation among multiple undifferentiated cells comprises: a step for detecting the amount of SALL3 mRNA expressed in the respective undifferentiated cells; and a step for rating the cells with the highest relative amounts of SALL3 mRNA expressed as having the highest tendency towards differentiation to ectodermal cells and rating the cells with the lowest relative amounts of SALL3 mRNA expressed as having the highest tendency towards differentiation to mesodermal cells or endodermal cells.

机译：提供了一种简便且省力的方法，用于评估未分化细胞之间的分化趋势。对多个未分化细胞之间的分化倾向进行评价的方法包括：检测在各个未分化细胞中表达的SALL3 mRNA的量的步骤;以及对具有相对高表达的SALL3 mRNA相对分化为外胚层细胞趋势的细胞进行评级的步骤，以及对具有相对低表达SALL3 mRNA的相对分化为中胚层细胞的趋势最高的细胞进行评级。内胚层细胞。

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公开/公告号WO2017171097A1

专利类型
公开/公告日2017-10-05

原文格式PDF
申请/专利权人 JAPAN HEALTH SCIENCES FOUNDATION;
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申请/专利号WO2017JP13952
发明设计人 KURODA TAKUYA;YASUDA SATOSHI;SATO YOJI;
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申请日2017-04-03
分类号C12Q1/68;C12N5/0735;C12N5/10;C12N15/09;
国家 WO
入库时间 2022-08-21 13:29:23

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