首页> 外国专利> MARKER FOR DETECTING MYOCARDIAL CELL DIFFERENTIATION ACTIVITY OF UNDIFFERENTIATED CELL, NUCLEIC ACID MOLECULE, PRIMER PAIR, KIT, INHIBITOR FOR MYOCARDIAL DIFFERENTIATION, METHOD FOR DETECTING MYOCARDIAL CELL DIFFERENTIATION ACTIVITY OF UNDIFFERENTIATED CELL, METHOD FOR ISOLATING CELL HAVING MYOCARDIAL DIFFERENTIATION ACTIVITY, METHOD FOR MONITORING MYOCARDIAL DIFFERENTIATION ACTIVITY OF UNDIFFERENTIATED CELL, AND METHOD FOR INHIBITING MYOCARDIAL DIFFERENTIATION OF UNDIFFERENTIATED CELL

MARKER FOR DETECTING MYOCARDIAL CELL DIFFERENTIATION ACTIVITY OF UNDIFFERENTIATED CELL, NUCLEIC ACID MOLECULE, PRIMER PAIR, KIT, INHIBITOR FOR MYOCARDIAL DIFFERENTIATION, METHOD FOR DETECTING MYOCARDIAL CELL DIFFERENTIATION ACTIVITY OF UNDIFFERENTIATED CELL, METHOD FOR ISOLATING CELL HAVING MYOCARDIAL DIFFERENTIATION ACTIVITY, METHOD FOR MONITORING MYOCARDIAL DIFFERENTIATION ACTIVITY OF UNDIFFERENTIATED CELL, AND METHOD FOR INHIBITING MYOCARDIAL DIFFERENTIATION OF UNDIFFERENTIATED CELL

机译：用于检测未分化细胞的心肌细胞分化活性的标记物，核酸分子，底漆对，试剂盒，用于心肌分化的抑制剂，用于检测心肌细胞分化度的方法，用于分化能力的鉴别方法未分化细胞的活性及抑制未分化细胞心肌分化的方法

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摘要

PROBLEM TO BE SOLVED: To provide a marker useful for precise and simple detection of myocardial differentiation activity of a cell, and also a nucleic acid molecule, a primer pair, a kit, an inhibitor for myocardial differentiation, a method for detecting myocardial differentiation activity of an undifferentiated cell, a method for isolating the cell having the myocardial differentiation activity, a method for monitoring the myocardial differentiation activity of the undifferentiated cell and a method for inhibiting the myocardial differentiation of the undifferentiated cell.SOLUTION: The marker includes a CMP (cardiomyogenesis predictor) gene showing a correlation with the myocardial differentiation activity of a cell, or its genetic product. The genetic marker is used for detecting the myocardial differentiation activity of an undifferentiated cell, and is a polynucleotide comprising a nucleotide sequence having a specific sequence, or its fragment.

机译：要解决的问题：提供一种标记物，可用于精确，简单地检测细胞的心肌分化活性，以及核酸分子，引物对，试剂盒，心肌分化抑制剂，检测心肌分化活性的方法未分化细胞的分离，分离具有心肌分化活性的细胞的方法，监测未分化细胞的心肌分化活性的方法和抑制未分化细胞的心肌分化的方法。解决方案：标记物包括CMP（显示出与细胞或其遗传产物的心肌分化活性相关的基因。遗传标记用于检测未分化细胞的心肌分化活性，并且是包含具有特定序列的核苷酸序列或其片段的多核苷酸。

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公开/公告号JP2013031448A

专利类型
公开/公告日2013-02-14

原文格式PDF
申请/专利权人 JAPAN HEALTH SCIENCE FOUNDATION;
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申请/专利号JP20120209759
发明设计人 SATO YOJI;HASEGAWA TETSUYA;YAMAGUCHI TERUHIDE;HOSONO TETSUJI;SATO MITSUTOSHI;
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申请日2012-09-24
分类号C12N15/09;C12Q1/04;C12Q1/68;C12N5/095;
国家 JP
入库时间 2022-08-21 17:00:33

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