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Use of molecular chaperones for enhanced production of recombinant secreted proteins in mammalian cells
Use of molecular chaperones for enhanced production of recombinant secreted proteins in mammalian cells
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机译:分子伴侣在哺乳动物细胞中增强重组分泌蛋白产生的用途
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摘要
A mammalian host cell for enhanced expression of a recombinant protein product, said mammalian cell having genetic material encoding the expression of said recombinant protein product and transformed with at least one expression vector comprising DNA encoding the calnexin chaperone protein, wherein said recombinant protein product is Factor VIII.
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