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Filamentous fungal cell with inactivated component from the selective autophagal signal pathway and method of use thereof

机译:选择性自噬信号通路中具有灭活成分的丝状真菌细胞及其使用方法

摘要

Disclosed are modified filamentous fungal cells in which the selective autophagy system of the filamentous fungal cell has been partially or completely inactivated, methods of making such genetically modified filamentous fungal cells, and methods for producing biological products of interest in such modified filamentous fungal cells. Also disclosed are genetically modified filamentous fungal cells having disrupted or deleted atg11 activity, methods of making such genetically modified filamentous fungal cells, and methods for producing biological products of interest in such modified filamentous fungal cells.
机译:公开了其中丝状真菌细胞的选择性自噬系统已部分或完全失活的修饰的丝状真菌细胞,制备此类基因修饰的丝状真菌细胞的方法以及在此类修饰的丝状真菌细胞中产生目的生物产物的方法。还公开了具有破坏或缺失的atg11活性的基因修饰的丝状真菌细胞,制备这种基因修饰的丝状真菌细胞的方法,以及在此类修饰的丝状真菌细胞中产生目的生物学产物的方法。

著录项

  • 公开/公告号DK2981546T3

    专利类型

  • 公开/公告日2017-02-06

    原文格式PDF

  • 申请/专利权人 NOVOZYMES A/S;

    申请/专利号DK20140715280T

  • 发明设计人 UDAGAWA HIROAKI;

    申请日2014-04-03

  • 分类号C07K14/38;

  • 国家 DK

  • 入库时间 2022-08-21 13:39:20

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