首页> 外国专利> Vaginal ring containing DHEA or DHEA sulfate and, optionally, an agent to modulate the release of the active principle, which can be used to increase the ovarian reserve in women and to relieve the symptoms associated with menopause.

Vaginal ring containing DHEA or DHEA sulfate and, optionally, an agent to modulate the release of the active principle, which can be used to increase the ovarian reserve in women and to relieve the symptoms associated with menopause.

机译:含有DHEA或DHEA硫酸盐以及可选地调节活性成分释放的阴道环,可用于增加女性的卵巢储备并缓解与更年期相关的症状。

摘要

Summary "vaginal ring containing DHEA or DHEA sulfate and, optionally, an agent to modulate the release of the active principle, which can be used to increase the ovarian reserve in women and to relieve the symptoms associated with the menopause," the invention refers to a vaginal ring of Li. Berau00e7u00e3o controlled including dehydroepiandrosterone (DHEA)Dehydroepiandrosterone sulfate (DHEAS) or a pharmacologically acceptable salt thereof as an active ingredient, and optionally, an agent modulating release of active principle, in which the quantity of the active principle is between 1 wt% and 32% by weight relative to the total weight of the is Stimulation, and the agent is selected from the modulator: polyvinylpyrrolidone K-30, lactose,Micro crystalline cellulose and sodium lauryl sulfate. The vaginal ring of this invention can be used to increase the ovarian reserve in women, to be used as a medicine in programmes of assisted reproduction and to relieve the symptoms associated with the menopause, such as symptoms of vulvar and vaginal atrophy and disfunu00e7u00e3 The sexual in post menopause.
机译:发明内容“含有DHEA或DHEA硫酸盐的阴道环,以及任选地调节活性成分释放的试剂,其可用于增加女性的卵巢储备并缓解与更年期有关的症状,”指李的阴道环。受控制的贝拉,包括脱氢表雄酮(DHEA),硫酸脱氢表雄酮(DHEAS)或其药理学上可接受的盐作为活性成分,以及任选地调节活性成分释放的试剂,其中活性成分的量为1 wt%相对于其总重量的50%和32%重量是刺激性的,并且该试剂选自调节剂:聚乙烯吡咯烷酮K-30,乳糖,微晶纤维素和月桂基硫酸钠。本发明的阴道环可用于增加女性的卵巢储备,在辅助生殖程序中用作药物,并缓解与更年期相关的症状,例如外阴和阴道萎缩和不适的症状。 u00e3绝经后的性生活。

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