首页> 外国专利> The sustained release antimicrobial antimicrobial sustained release, urinary catheter, method to make sustained release antimicrobial cannula, method for making a urinary antimicrobial catheter cannula, sustained release, method for making a CA Teter sustained release antimicrobial, method of catheterization of a patient, and,Sustained release bactericidal catheter.

The sustained release antimicrobial antimicrobial sustained release, urinary catheter, method to make sustained release antimicrobial cannula, method for making a urinary antimicrobial catheter cannula, sustained release, method for making a CA Teter sustained release antimicrobial, method of catheterization of a patient, and,Sustained release bactericidal catheter.

机译：持续释放抗微生物剂抗微生物持续释放，导尿管，制造持续释放抗微生物套管的方法，制造尿液抗微生物导管套管的方法，持续释放，CA Teter持续释放抗微生物剂的制备方法，患者的导管插入方法以及缓释杀菌导管。

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Summary of sustained release antimicrobial cannula, sustained release antimicrobial urinary catheter, method to make sustained release antimicrobial cannula, method for making a urinary antimicrobial catheter cannula, method to make sustained release. A sustained release antimicrobial catheter, method of catheterization of a patient, and,Sustained release bactericidal catheter cannula or catheter for residence in sustained release antimicrobial treatment of a part of a human body through which aqueous biological fluids can pass. The antimicrobial catheter including a tube cannula for having an inner surface, which defines an inner lumen, and an outer surface.The tube has a polymeric matrix and an antimicrobial agent that resides within at least a portion of the polymeric matrix.The polymeric matrix includes silicone rubber cured and the antimicrobial agent is a compound of nitrofuran divided accurately, an antifungal of parabeno, or combinations of these, which is soluble in water and efficiently to prevent the proliferation of certain microbes in an environment Quoso, otherwise, supportive of growth.When dissolved in aqueous environment at the limit of its solubility in it at 37 u00b0 C. The solubility of the antimicrobial agent is, for example, to about 0.5% by weight or less at a pH of about 6 and a temperature of about 25 u00b0 C.The antimicrobial agent can spread from the polymeric matrix and an aqueous biological environment when the polymeric matrix comes into contact with the aqueous biological environment.In one implementation, at least a portion of the polymeric matrix finite, next to the outer surface.It includes a quantity of about 10 to about 60% by weight of the antimicrobial agent and the amount of antimicrobial agent, and its solubility cooperate to provide a potential for dissemination of sustained its release for a period of not less than about three weeks for the use in Rmal cannula within the human body.Methods for making the sustained release antimicrobial cannula and catheterization of a patient are also disclosed. 1 / 2

机译：持续释放抗微生物套管的概述，持续释放抗微生物导尿管，制造持续释放抗微生物套管的方法，制造尿液抗微生物导尿管套管的方法，进行持续释放的方法。缓释抗菌导管，患者的导管插入方法以及缓释杀菌导管插管或用于驻留在人体的一部分的缓释抗菌治疗中的导管，水性生物流体可通过该导管进行治疗。所述抗菌导管包括用于具有限定内腔的内表面和外表面的管套管。所述管具有聚合物基质和驻留在所述聚合物基质的至少一部分内的抗微生物剂。硫化的硅橡胶和抗菌剂是硝基呋喃的化合物，可以精确分解，可以是对伞菌的抗真菌药，也可以是它们的组合，它们可溶于水并能有效地防止某些微生物在Quoso环境中繁殖，否则会促进生长。当在37℃下以在水中的溶解度极限溶解于水性环境中时。抗微生物剂的溶解度例如在约6的pH和约25的温度下为约0.5重量％以下。当聚合物基质与水性生物环境接触时，抗菌剂会从聚合物基质和水性生物环境中扩散在一种实施方式中，至少部分聚合物基质是有限的，紧挨着外表面。其包括约10至约60重量％的抗微生物剂和一定量的抗微生物剂，并且其溶解度相互配合。提供了在人体中的Rmal套管中散布持续释放不少于三周的潜力的可能性。还公开了制备持续释放的抗菌套管和患者导管的方法。 1 / 2

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公开/公告号BR112014010305A2

专利类型
公开/公告日2017-04-18

原文格式PDF
申请/专利权人 ROCHESTER MEDICAL CORPORATION;
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申请/专利号BR20141110305
发明设计人 ANTHONY J. CONWAY;
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申请日2012-12-06
分类号C08L83/04;A61L29/06;A61L29/08;A61L29/16;
国家 BR
入库时间 2022-08-21 13:40:34

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