Sustained Release of Antimicrobial Drugs from Graphene Oxide Immobilized Titanium Surfaces for the Enhanced Antibacterial Activity

机译：从氧化石墨烯固定的钛表面持续释放抗菌药物，以增强抗菌活性

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In this study, the phenol containing GO was simply immobilized on a TiO_2 surface via single-step tyrosinase-mediated reaction in mild conditions. We used the GO-immobilized TiO_2 substrate not only as an antimicrobial agent but also as a vehicle for delivering antimicrobial drugs. In addition, the immobilized surfaces were non-toxic toward the human cells. In conclusion, the release of doxycycline hyclate in a sustained manner from GO immobilized surfaces is expected to solve the pressing need for enhanced infection control.

机译：在这项研究中，在温和条件下，通过一步酪氨酸酶介导的反应将含苯酚的GO固定在TiO_2表面上。我们不仅将GO固定化的TiO_2基质用作抗菌剂，而且还将其用作递送抗菌药物的载体。另外，固定的表面对人细胞无毒。总之，从固定化GO的表面持续释放强力霉素盐酸盐有望解决增强感染控制的迫切需求。

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《Society for Biomaterials annual meeting and exposition》|2018年|345-345|共1页
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Dieu Linh Tran; Thai Thanh Hoang Thi; Phuong Le Thi; Ki Dong Park;
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2. Graphene oxide immobilized surfaces facilitate the sustained release of doxycycline for the prevention of implant related infection [J] . Dieu Linh Tran, Phuong Le Thi, Thai Thanh Hoang Thi, Colloids and Surfaces, B. Biointerfaces . 2019,第期

机译：石墨烯氧化物固定化表面有助于持续释放的强霉素用于预防植入物相关感染
3. Enhanced catalytic and antibacterial activities of silver nanoparticles immobilized on poly(N-vinyl pyrrolidone)-grafted graphene oxide [J] . Singh Shikha, Gundampati Ravi Kumar, Mitra Kheyanath, RSC Advances . 2015,第100期

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4. Sustained Release of Antimicrobial Drugs from Graphene Oxide Immobilized Titanium Surfaces for the Enhanced Antibacterial Activity [C] . Dieu Linh Tran, Thai Thanh Hoang Thi, Phuong Le Thi, Society for Biomaterials annual meeting and exposition . 2018

机译：从石墨烯氧化物固定的钛表面持续释放抗菌药物，用于增强抗菌活性
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机译：具有钯，表面酸度和氧化钛（IV），氧化钨（VI）/氧化钛（IV）和氧化钼（VI）/氧化钛（IV）的表面酸性和光催化活性的氧化钛（IV）光催化剂。
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机译：壳聚糖-miRNA通过层逐层方法官能化微孔氧化钛表面，其具有持续释放曲线，用于增强骨质发生活性

Sustained Release of Antimicrobial Drugs from Graphene Oxide Immobilized Titanium Surfaces for the Enhanced Antibacterial Activity

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