首页> 外国专利> Glycomimetics to inhibit pathogen-host interactions

Glycomimetics to inhibit pathogen-host interactions

机译：糖代谢抑制剂抑制病原体与宿主的相互作用

页面导航

摘要
著录项
相似文献

摘要

The present invention relates to novel glycomimetic compounds that are rationally designed to inhibit the binding of various pathogens to cell surface sialylated galactose and methods of use thereof. Specifically sialic acid glycosides and C-glycosides are disclosed that form a lactam ring structure or a cyclic ether/amine ring structure with the adjacent monosaccharide residue.

机译：本发明涉及被合理设计以抑制各种病原体与细胞表面唾液酸化半乳糖结合的新型拟糖化合物及其使用方法。具体地，公开了与相邻的单糖残基形成内酰胺环结构或环状醚/胺环结构的唾液酸糖苷和C-糖苷。

著录项

公开/公告号US9605014B2

专利类型
公开/公告日2017-03-28

原文格式PDF
申请/专利权人 UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC.;NATIONAL UNIVERSITY OF IRELAND GALWAY;GLYCOSENSORS AND DIAGNOSTICS LLC.;
展开▼

申请/专利号US201314385312
发明设计人 ROBERT J. WOODS;PAUL V. MURPHY;LORETTA YANG;HANNAH M. K. SMITH;JENIFER HENDEL;
展开▼

申请日2013-03-14
分类号C07H17/04;C07H15/20;C07H17/02;C07H19/01;C07H19/02;C07H19/04;C07H19/24;C07H15/04;C07D455/02;G06F19/10;
国家 US
入库时间 2022-08-21 13:42:52

相似文献

专利
外文文献
中文文献