首页> 外国专利> Monoclonal antibodies directed against a novel pathogenic west African human immunodeficiency virus type 2 (HIV-2) group F isolate

Monoclonal antibodies directed against a novel pathogenic west African human immunodeficiency virus type 2 (HIV-2) group F isolate

机译:针对新型致病性西非2型人类免疫缺陷病毒(HIV-2)F组分离株的单克隆抗体

摘要

Isolated monoclonal antibodies that bind to HIV-2 isolate NWK08F are provided. In some embodiments, the antibodies bind a polypeptide comprising the HIV-2NWK08F Env, Pol, or Nef proteins, or fragments thereof, respectively. Antigen-binding fragments and humanized versions of the antibody are also provided.
机译:提供了与HIV-2分离株NWK08F结合的分离的单克隆抗体。在一些实施方案中,抗体分别结合包含HIV-2NWK08F Env,Pol或Nef蛋白或其片段的多肽。还提供了抗体的抗原结合片段和人源化形式。

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