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TRUNCATED VARIANT OF THE MAMMALIAN TARGET FOR RAPAMYCIN (mTOR) PROTEIN

机译:雷帕霉素(mTOR)蛋白哺乳动物靶标的截断变异

摘要

The invention relates to mTORbeta, a splice form of mTOR, nucleic acids encoding mTOR beta, and antibodies against mTOR beta. The invention also relates to methods of producing mTOR beta and methods of screening for an agent that modulates mTOR beta expression and/or activity. The invention further relates to a method of treating a disease associated with aberrant expression of mTOR beta by administration of an agent that alters mTOR activity and/or expression.
机译:本发明涉及mTORβ,mTOR的剪接形式,编码mTORβ的核酸和针对mTORβ的抗体。本发明还涉及产生mTORβ的方法和筛选调节mTORβ表达和/或活性的试剂的方法。本发明进一步涉及通过给予改变mTOR活性和/或表达的药剂来治疗与mTORβ的异常表达有关的疾病的方法。

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