首页> 外国专利> METHOD FOR SIMULTANEOUSLY DETECTING FLUORESCENCE AND RAMAN SIGNALS FOR MULTIPLE FLUORESCENCE AND RAMAN SIGNAL TARGETS, AND MEDICAL IMAGING DEVICE FOR SIMULTANEOUSLY DETECTING MULTIPLE TARGETS USING THE METHOD

METHOD FOR SIMULTANEOUSLY DETECTING FLUORESCENCE AND RAMAN SIGNALS FOR MULTIPLE FLUORESCENCE AND RAMAN SIGNAL TARGETS, AND MEDICAL IMAGING DEVICE FOR SIMULTANEOUSLY DETECTING MULTIPLE TARGETS USING THE METHOD

机译:同时检测多个荧光和拉曼信号目标的荧光和拉曼信号的方法,以及使用该方法同时检测多个目标的医学成像装置

摘要

Provided are a method for simultaneously detecting fluorescence and Raman signals for multiple fluorescence and Raman signal targets, and a medical imaging device for simultaneously detecting multiple targets using the method. The method includes: injecting at least one marker particle comprising Raman markers and receptors into the body of an animal, which can be a human; irradiating a laser beam onto the body of the animal; and detecting the optical signals emitted by the marker particle after the irradiation of the laser beam separately as fluorescence signals and Raman signals. The simultaneous detection of multiple targets may be performed even without scanning optical signals emitted by the marker particle individually with different optical fibers. As an examination may be performed by injecting surface-enhanced Raman marker particles, weak Raman signals may be augmented so as to obtain a more accurate diagnosis result in real time.
机译:提供一种用于同时检测多个荧光和拉曼信号目标的荧光和拉曼信号的方法,以及使用该方法同时检测多个目标的医学成像装置。该方法包括:将至少一种包含拉曼标记和受体的标记颗粒注射到动物体内,该动物可以是人类。将激光束照射到动物的身体上;分别检测激光束照射后标记颗粒发射的光信号作为荧光信号和拉曼信号。即使不使用不同的光纤分别扫描由标记颗粒发射的光信号,也可以同时检测多个目标。由于可以通过注入表面增强的拉曼标记颗粒进行检查,因此可以增强微弱的拉曼信号,以便实时获得更准确的诊断结果。

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