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Novel Combination of Naturally Occurring Compounds to Assist With Suspected Mycobacterial Infections Related to Autoimmune Conditions

机译：天然存在的化合物的新型组合，可协助与自身免疫性疾病有关的疑似分枝杆菌感染

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摘要

The novel aspect of this invention is that it is a unique formulation of naturally occurring compounds with a unique intention to assist the concerns associated with autoimmune conditions, mainly inflammatory bowel disease (collectively Crohn's, ulcerative colitis, irritable bowel syndrome), Type 1 diabetes, Multiple sclerosis, Psoriasis and the suspected infection of the pathogen Mycobacterium avium sub-species paratuberculosis (MAP). Furthermore, its intent is to address the lack of treatment options available for those with aforementioned autoimmune conditions. Specifically, to offer an alternative option that does not pose the amount of negative side effects that may be associated with contemporary treatment methods. The invention will offer a treatment method that is lower in cost as persons with autoimmune conditions conventional treatment methods costs are rising even under most insurance provider's coverage. In addition, the invention offers an available method without the barriers to care most people with autoimmune conditions may encounter. The invention will provide educational information to persons with autoimmune conditions to offer an individual choice in methods of treatment. The invention will offer persons with autoimmune conditions a variety of options as said invention can be utilized con-currently with conventional treatment methods.

机译：本发明的新颖之处在于，它是天然存在的化合物的独特配方，其独特意图旨在解决与自身免疫性疾病（主要是炎症性肠病（统称克罗恩氏病，溃疡性结肠炎，肠易激综合症），1型糖尿病，多发性硬化症，牛皮癣和疑似病原体禽分枝杆菌亚种副结核病（MAP）。此外，其目的是解决缺乏具有上述自身免疫性疾病的人可用的治疗选择的问题。具体而言，提供一种不会引起与现代治疗方法相关的负面副作用的替代选择。本发明将提供一种成本较低的治疗方法，因为患有自身免疫病的人常规治疗方法的成本甚至在大多数保险提供者的承保范围内也在增加。另外，本发明提供了一种可用的方法，其没有障碍来照顾大多数患有自身免疫病的人可能遇到的障碍。本发明将为患有自身免疫病的人提供教育信息，以提供治疗方法的个体选择。本发明将为患有自身免疫病的人提供多种选择，因为所述发明可以与常规治疗方法同时使用。 展开▼

著录项

公开/公告号US2017173059A1

专利类型

公开/公告日2017-06-22

原文格式PDF

申请/专利权人 NICHOLAS MAGRONE JR.;
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申请/专利号US201615354975

发明设计人 NICHOLAS MAGRONE JR.;
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申请日2016-11-17

分类号A61K31/704;A61K31/216;A61K31/085;A61K31/045;A61K36/54;A61K31/05;A61K31/015;A61K36/53;A61K31/105;A61K31/198;A61K36/8962;A61K31/56;A61K36/23;A61K31/4375;A61K31/473;A61K36/29;A61K36/324;A61K31/07;A61K31/593;A61K9/48;A61K9/00;A61K9/20;A61K31/11;

国家 US

入库时间 2022-08-21 13:51:10

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机译：在怀疑患有感染的哺乳动物受试者中治疗弹状病毒感染的方法，在哺乳动物受试者中治疗自身免疫疾病的方法，在哺乳动物受试者中治疗炎症的方法，通过受体途径在细胞中鉴定信号传导调节剂的方法如“ 4”，选择用于治疗传染病的化合物的方法，选择用于治疗自身免疫疾病的化合物的方法，选择用于治疗炎症的化合物的方法，转基因非人类动物，细胞或细胞系，体外方法类工具4或tram-trif受体信号传导活性调节剂的选择以及体内选择类工具4或tram-trif受体信号传导活性调节剂的方法

4. compound, composition, pharmaceutically acceptable salt of a compound, combination, pharmaceutical formulation, methods for killing a mycobacterium and / or inhibiting replication of disease causing mycobacteria in an animal, for treating a mycobacterial infection in an animal and for treating a disease resulting from a mycobacterial infection of a mammal, and use of a compound. [P] . BR112017017211A2 . 2018-04-03

机译：化合物，组合物，化合物的药学上可接受的盐，组合，药物制剂，在动物中杀死分枝杆菌和/或抑制引起分枝杆菌的疾病复制，在动物中治疗分枝杆菌感染以及治疗由细菌引起的疾病的方法哺乳动物的分枝杆菌感染，以及化合物的用途。

5. compound, pharmaceutically acceptable salt of a compound, pharmaceutical composition, combination, pharmaceutical formulation, methods for exterminating a mycobacterium and / or inhibiting mycobacterial replication, and for treating an infection and disease, and use of a compound [P] . BR112016002651A2 . 2017-08-01

机译：化合物，化合物的药学上可接受的盐，药物组合物，组合，药物制剂，消灭分枝杆菌和/或抑制分枝杆菌复制以及治疗感染和疾病的方法，以及化合物的用途

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