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How improvement of detection sensitivity in the detection of anti-thrombopoietin antibodies, detection method and kit of immune thrombocytopenia

机译:如何提高抗血小板生成素抗体的检测灵敏度,免疫性血小板减少症的检测方法和试剂盒

摘要

PROBLEM TO BE SOLVED: To provide a detection method of an anti-TPO antibody, a detection method of immune thrombocytopenia, a kit for detecting an anti-TPO antibody in a biological sample, and a kit for detecting immune thrombocytopenia which have improved detection sensitivity.SOLUTION: There are provided a detection method of an anti-TPO antibody in a biological sample includes: a process of allowing TPO and the biological sample to contact; and a process of detecting bond between the anti-TPO antibody and the TPO, in which the TPO is expressed in a mammalian cell expression system; a detection method of immune thrombocytopenia; a kit for detecting the anti-TPO antibody in the biological sample including the TPO expressed in the mammalian cell expression system; and a kit for detecting immune thrombocytopenia the TPO expressed in the mammalian cell expression system.SELECTED DRAWING: None
机译:解决的问题:提供具有提高的检测灵敏度的抗-TPO抗体的检测方法,免疫性血小板减少症的检测方法,用于检测生物样品中的抗-TPO抗体的试剂盒以及用于检测免疫性血小板减少症的试剂盒。解决方案:提供了一种生物样品中抗TPO抗体的检测方法,包括:使TPO与生物样品接触的过程;检测抗TPO抗体与TPO之间的键的方法,其中TPO在哺乳动物细胞表达系统中表达;免疫性血小板减少症的检测方法;用于检测包括在哺乳动物细胞表达系统中表达的TPO在内的生物样品中的抗TPO抗体的试剂盒;以及用于检测哺乳动物细胞表达系统中表达的TPO的免疫性血小板减少症的试剂盒。

著录项

  • 公开/公告号JP6085746B2

    专利类型

  • 公开/公告日2017-03-01

    原文格式PDF

  • 申请/专利权人 学校法人北里研究所;

    申请/专利号JP20140163570

  • 发明设计人 佐藤 隆司;

    申请日2014-08-11

  • 分类号G01N33/53;G01N33/543;

  • 国家 JP

  • 入库时间 2022-08-21 13:56:55

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