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METHOD FOR PREDICTION OF HEAVY PURULENT TRACHEOBRONCHITIS IN THERMOINHALATION LESION OF AIRWAY

机译:气管热吸入性病变中重度气管支气管炎的预测方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, particularly to fibre-optic bronchoscopy, and describes method for prediction of severe purulent tracheobronchitis developing with thermo-inhaling damage of respiratory tract by chemiluminescence. Method is characterised by that during bronchoscopy sampling of mucosal biopsy materials is performed, in which light sum of Fe2+ - induced chemiluminescence (Sind-1), H2O2 - induced luminol-dependent chemiluminescence (Sind-2) and maximum amplitude of H2OH2 - induced luminol-dependent fluorescence (H) are determined. If value of Sind-1 is 0.500 standard units and more, Sind-2 is 0.400 standard units and more and H is 0.300 standard units and more, developing of severe purulent tracheobronchitis of III degree of intensity of inflammation is predicted, if obtained simultaneously on all three values Sind-1 is 0.499 standard units and less, Sind-2 is 0.399 standard units and less and H is 0.299 standard units and less shows developing of catarrhal or purulent tracheobronchitis of I-II degree of intensity of inflammation is predicted.;EFFECT: disclosed method enables fast (within 30 minutes) and early prediction of purulent tracheobronchitis developing after thermo-inhaling damage of respiratory tract and proving necessity of performing of repeated daily remedial bronchoscopies.;1 cl, 1 tbl, 4 ex
机译:发明领域本发明涉及药物,特别是涉及纤维支气管镜检查,并描述了用于预测严重化脓性气管支气管炎的方法,该化脓性气管支气管炎由化学发光引起呼吸道热吸入损伤。该方法的特征在于,在支气管镜检查期间,对粘膜活检材料进行采样,其中Fe 2 + -诱导的化学发光(Sind-1),H 2 O < Sub> 2 -诱导的鲁米诺依赖性化学发光(Sind-2)和H 2 OH 2 -诱导的鲁米诺依赖性荧光(H)的最大幅度为决心。如果Sind-1的值等于或大于0.500标准单位,Sind-2的等于或大于0.400标准单位,H等于或大于0.300标准单位,则如果同时获得Sind-1的严重化脓性气管支气管炎,其炎症强度为III级。这三个值的Sind-1均为0.499标准单位及以下,Sind-2为0.399标准单位及以下,H为0.299标准单位及以下,表明预测了I-II炎症性程度的卡他性或化脓性气管支气管炎的发展。效果:公开的方法能够快速(30分钟内)并早期预测化脓性气管支气管炎,发生在热吸入性呼吸道损伤后,并证明有必要每天重复进行补救性支气管镜检查; 1 cl,1 tbl,4 ex

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