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Improvement method of gene network using domain-specific phylogenetic profiles similarity

机译:利用特定域系统发育谱相似性的基因网络改良方法

摘要

The present invention relates to a method for improving gene networks using domain-specific PPS. By the method according to the present invention, it is possible to measure domain-specific PPS for two genes that are mutually dependent on the signal transduction pathway. The pathway of the signal transduction in the living organism of the gene can be effectively reconstructed using the domain specific PPS for the gene according to the present invention. In addition, it is possible to accurately measure the similarity between the phylogenetic profiles of the common-inherited genes by incorporating the domain-specific PPS-based gene network of the present invention, The gene can be predicted.
机译:本发明涉及使用域特异性PPS改善基因网络的方法。通过根据本发明的方法,可以测量两个相互依赖信号转导途径的基因的结构域特异性PPS。使用根据本发明的基因的结构域特异性PPS,可以有效地重建基因在生物体内的信号转导途径。另外,通过结合本发明的基于域特异性PPS的基因网络,可以准确地测量共同遗传基因的系统发育谱之间的相似性,从而可以预测该基因。

著录项

  • 公开/公告号KR101636995B1

    专利类型

  • 公开/公告日2016-07-21

    原文格式PDF

  • 申请/专利权人 연세대학교 산학협력단;

    申请/专利号KR20140012940

  • 发明设计人 이인석;신준하;

    申请日2014-02-05

  • 分类号G06F19/12;

  • 国家 KR

  • 入库时间 2022-08-21 14:12:18

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