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IMPROVEMENT METHOD OF GENE NETWORK USING DOMAIN-SPECIFIC PHYLOGENETIC PROFILES SIMILARITY
IMPROVEMENT METHOD OF GENE NETWORK USING DOMAIN-SPECIFIC PHYLOGENETIC PROFILES SIMILARITY
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机译:基于域特定系统发育相似度的基因网络改进方法
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摘要
The present invention relates to a method for improving a gene network using a domain-specific PPS. The domain-specific PPS for two mutual dependent genes is measured in a signal transmission path by the method according to the present invention. The signal transmission path of the gene in a body is efficiently reconstructed by using the domain-specific PPS for the gene according to the present invention. Also, similarity between the phylogenetic profiles of the genes which are commonly inherited is accurately measured by combining the gene network based on the domain-specific PPS according to the present invention. The gene related to the diseases of a human is predicted by using the constructed gene network.
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