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Mosapride citrate sustained-release matrix formulation dispersed by pellet and preparing the method thereof

机译:颗粒分散的枸s酸莫沙必利缓释基质制剂及其制备方法

摘要

In the case of the capsule preparation containing the simfried citrate of the present invention, there is no fear of arrhythmia and cardiogenic sudden death, and there is no side effects such as central nervous system side effect and hyperprolactinemia, so that it can be safely used. In addition, as compared with the conventional sustained-release matrix preparation, the elution time can be controlled relatively accurately, and the elution pattern exhibits a pattern similar to a zero order.
机译:在含有本发明的辛酸柠檬酸盐的胶囊剂的情况下,无需担心心律不齐和心源性猝死,并且不存在中枢神经系统副作用和高泌乳素血症等副作用,因此可以安全地使用。 。另外,与常规的缓释基质制剂相比,洗脱时间可以相对准确地控制,并且洗脱图案表现出类似于零级的图案。

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