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NON-INVASIVE METHOD FOR PREDICTION OF OPIOID-ANALGESIA AND OPIOID-BLOOD-CONCENTRATIONS
NON-INVASIVE METHOD FOR PREDICTION OF OPIOID-ANALGESIA AND OPIOID-BLOOD-CONCENTRATIONS
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机译：非侵入性方法预测阿片样物质的镇痛作用和阿片样物质的血药浓度
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摘要
the present invention are, for example, conventional (palliative) of the blood level of the analgesic and opioid drugs in the patient received the treatment of pain during the treatment in a non-invasive method and apparatus for predicting or monitoring will. The method of the present invention one or more of the patient, and a preferably two or more surrogate markers measured. According to the invention, the surrogate markers are correlated with the level of the opioid analgesic from the service object, and thus for the treatment of analgesia and provides a non-invasive method for predicting and monitoring. In addition, the opioid in the blood of the subject-matter density surrogate markers that were identified. Accordingly, the present invention provides a valuable clinical tool for evaluating and controlling the treatment of pain with opioids. Device, as well as the prediction method for use in a medical treatment, such as pain, and a suitable apparatus are disclosed for performing the method of the present invention.
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