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Combination of sPLA2 activity and cardiovascular risk factors OxPL / apoB for diagnosis / prognosis of a disease / cardiovascular event

机译：sPLA2活性和心血管危险因素OxPL / apoB的组合用于疾病/心血管事件的诊断/预后

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摘要

A method to identify a subject that has or is at risk of having or developing a cardiovascular disease and / or a cardiovascular event, comprising: - measuring, in a sample obtained from said subject, at least two cardiovascular risk factors: a ) secreted phospholipase A2 activity (sPLA2) and b) apolipoprotein B-100 particles oxidized phospholipids (OxPL / apoB), - combining said measurements, the combined value of sPLA2 and OxPL / apoB activity is an indication that it has or is in risk of having or developing a cardiovascular disease and / or cardiovascular event.

机译：一种鉴定患有或处于患有或处于患有心血管疾病和/或心血管事件的风险中的受试者的方法，该方法包括：-在从所述受试者获得的样品中测量至少两种心血管疾病危险因素：a）分泌的磷脂酶A2活性（sPLA2）和b）载脂蛋白B-100颗粒氧化了磷脂（OxPL / apoB），-结合上述测量，sPLA2和OxPL / apoB活性的组合值表明其具有或有患上或发展中的危险心血管疾病和/或心血管事件。

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公开/公告号ES2556759T3

专利类型
公开/公告日2016-01-20

原文格式PDF
申请/专利权人 INSERM - INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;UNIVERSITÉ PARIS DIDEROT - PARIS 7;
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申请/专利号ES20090737386T
发明设计人 MALLAT ZIAD;TEDGUI ALAIN;TSIMIKAS SOTIRIOS;WITZTUM JOSEPH;
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申请日2009-10-02
分类号G01N33/573;G01N33/68;G01N33/92;
国家 ES
入库时间 2022-08-21 14:22:18

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