NOVEL GLITAZONES AS PPAR-α AND PPAR-γ AGONISTS AND α-GLUCOSIDASE INHIBITORS

• 1. PPAR-δ激动剂在治疗线粒体肌病中的用途 [P] . 中国专利： CN113710683A . 2021-11-26
• 2. 用于提高HDL-C、降低LDL-C和降低胆固醇的PPAR-δ激动剂苯并氮杂*-氧基乙酸衍生物 [P] . 中国专利： CN101479008B . 2013.07.17
• 3. PHARMACEUTICAL COMPOSITION COMPRISING AN SGLT2 INHIBITOR AND A PPAR- GAMMA AGONIST AND USES THEREOF [P] . 美国专利： US2014088027A1 . 2014-03-27

  机译： 包含SGLT2抑制剂和PPAR-γ激动剂的药物组合物及其用途

• 4. PHARMACEUTICAL COMPOSITION COMPRISING AN SGLT2 INHIBITOR AND A PPAR- GAMMA AGONIST AND USES THEREOF [P] . 欧洲知识产权局专利： EP2552442A1 . 2013-02-06

  机译： 包含SGLT2抑制剂和PPAR-γ激动剂的药物组合物及其用途

• 5. PHARMACEUTICAL COMPOSITION COMPRISING AN SGLT2 INHIBITOR AND A PPAR- GAMMA AGONIST AND USES THEREOF [P] . 世界知识产权组织专利： WO2011120923A1 . 2011-10-06

  机译： 包含SGLT2抑制剂和PPAR-γ激动剂的药物组合物及其用途

• 1. Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking [J] . Suganya Murugesu, Zalikha Ibrahim, Qamar Uddin Ahmed, 药物分析学报（英文） . 2019,第002期
• 2. Gene set enrichment analysis of alpha-glucosidase inhibitors from Ficus benghalensis [J] . Pukar Khanal, B.M. Patil 亚太热带生物医学杂志（英文版） . 2019,第006期
• 3. Gene set enrichment analysis of alpha-glucosidase inhibitors from Ficus benghalensis [J] . Pukar Khanal, BMPatil 亚太热带生物医学杂志：英文版 . 2019,第006期
• 4. Agonists of PPAR-α, PPAR-γ, and RXR inhibit the formation of foam cells from macrophages in mice with inflammation [J] . DushkinM.I., KhoshchenkoO.M., PosokhovaE.N., Bulletin of experimental biology and medicine . 2007,第5期
• 5. PPAR-α Agonist Fenofibrate Prevented Diabetic Nephropathy by Inhibiting M1 Macrophages via Improving Endothelial Cell Function in db/db Mice [J] . Xiaomeng Feng, Xia Gao, Shuo Wang, Frontiers in Medicine . 2021,第a期
• 6. PPAR-α agonist regulates amyloid-β generation via inhibiting BACE-1 activity in human neuroblastoma SH-SY5Y cells transfected with APPswe gene [J] . DepartmentofNeurologyTheFirstAffiliatedHospitalofChongqingMedicalUniversity, SpecialWardsTheAffiliatedChildren鈥檚HospitalofChongqingMedicalUniversity Molecular and Cellular Biochemistry: An International Journal for Chemical Biology . 2015,第1a2期
• 7. FGF21 mediates corticosteroid-related bone mass loss through PPAR-$gamma$ [C] . Yaxin Guan, Jingshan Huang, Shengting Huang, IEEE International Conference on Bioinformatics and Biomedicine . 2019
• 8. Elucidating the Role of Peroxisome Proliferator-activated Receptor (PPAR-δ) in Microglia Cell Function During Experimental Autoimmune Encephalomyelitis (EAE) [D] . Doroshenko, Ellinore 2019
• 9. PPAR-α Agonist Fenofibrate Prevented Diabetic Nephropathy by Inhibiting M1 Macrophages via Improving Endothelial Cell Function in db/db Mice [O] . Xiaomeng Feng, Xia Gao, Shuo Wang, 2021
• 10. Combination of PPAR-α Agonist and DPP-4 Inhibitor: A Novel Therapeutic Approach in the Management of Diabetic Nephropathy [O] . Mandeep Kumar Arora 2013

• 1. Activation of PPAR-γ Inhibits Differentiation of Rat Osteoblasts by Reducing Expression of Connective Tissue Growth Factor [J] . Wei-wei YU ,Qin XIA ,Yan WU . 华中科技大学学报（医学）（英德文版） . 2014,第005期
• 2. Mangiferin ameliorates hyperglycemia by inhibiting oxidation and α-glucosidase activity [J] . Chi-Chi He1 ,Zhuo Luo2 ,Lu-Lu Wang2 . TMR现代中药 . 2018,第001期
• 3. PPAR-γ激动剂对肾小管上皮细胞趋化因子表达的影响 [C] . 宋艳芳 ,林青 ,祝先进 . 第一次全国中西医结合检验医学学术会议 . 2014
• 4. PPAR-γ激动剂对肾病综合征大鼠血清血管生成素样蛋白4及甘油三酯的影响 [A] . 林君杰 . 2018