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首页> 外国专利> METHOD AND APPARATUS FOR QUANTITATIVE AND DEPTH RESOLVED HYPERSPECTRAL FLUORESCENCE AND REFLECTANCE IMAGING FOR SURGICAL GUIDANCE

METHOD AND APPARATUS FOR QUANTITATIVE AND DEPTH RESOLVED HYPERSPECTRAL FLUORESCENCE AND REFLECTANCE IMAGING FOR SURGICAL GUIDANCE

机译：定量和深度分辨超光谱荧光和反射成像的方法和装置

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An imaging system, such as a surgical microscope, laparoscope, or endoscope or integrated with these devices, includes an illuminator providing patterned white light and/or fluorescent stimulus light. The system receives and images light hyperspectrally, in embodiments using a hyperspectral imaging array, and/or using narrowband tunable filters for passing filtered received light to an imager. Embodiments may construct a 3-D surface model from stereo images, and will estimate optical properties of the target using images taken in patterned light or using other approximations obtained from white light exposures. Hyperspectral images taken under stimulus light are displayed as fluorescent images, and corrected for optical properties of tissue to provide quantitative maps of fluorophore concentration. Spectral information from hyperspectral images is processed to provide depth of fluorophore below the tissue surface. Quantitative images of fluorescence at depth are also prepared. The images are displayed to a surgeon for use in surgery.
机译：诸如外科手术显微镜，腹腔镜或内窥镜的成像系统或与这些设备集成的成像系统包括提供图案化的白光和/或荧光刺激光的照明器。在使用高光谱成像阵列和/或使用窄带可调谐滤光器的实施例中，系统将高光谱的光接收并成像，以将滤波后的接收光传递至成像器。实施例可以从立体图像构造3-D表面模型，并且将使用在图案化光中拍摄的图像或使用从白光曝光获得的其他近似来估计目标的光学特性。在刺激光下拍摄的高光谱图像显示为荧光图像，并针对组织的光学特性进行校正以提供荧光团浓度的定量图。处理来自高光谱图像的光谱信息以提供组织表面以下的荧光团深度。还准备了深度荧光的定量图像。图像显示给外科医生用于手术。

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