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DISCSLARGEHOMOLOG (DLG) Treatment of DLG-related diseases by inhibition of natural antisense transcripts on DLG1

机译:DISCSLARGEHOMOLOG(DLG)通过抑制DLG1上的天然反义转录本来治疗DLG相关疾病

摘要

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Discs large homolog (DLG), in particular, by targeting natural antisense polynucleotides of Discs large homolog (DLG). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of DLG.
机译:本发明涉及反义寡核苷酸,其特别是通过靶向Discs Large同源物(DLG)的天然反义多核苷酸来调节Discs Large同源物(DLG)的表达和/或功能。本发明还涉及这些反义寡核苷酸的鉴定及其在治疗与DLG表达有关的疾病和病症中的用途。

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