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Method for producing induced pluripotent stem cells using embryonic stem cell-derived microvesicles

机译:使用源自胚胎干细胞的微泡生产诱导多能干细胞的方法

摘要

Provided is a method of dedifferentiating somatic cells using embryonic stem cell-derived microvesicles. Particularly, a method of preparing induced pluripotent stem cells by treating a composition including embryonic stem cell-derived microvesicles to the somatic cells. According to the method of preparing induced pluripotent stem cells, the dedifferentiation of the somatic cells may be efficiently performed without side effects using the embryonic stem cell-derived microvesicles, and moreover, the method is expected to be very useful in developing a cell therapy product having immunocompatibilities by individuals.
机译:提供了一种使用源自胚胎干细胞的微泡使体细胞去分化的方法。特别地,一种通过将包含胚胎干细胞衍生的微泡的组合物处理到体细胞中来制备诱导多能干细胞的方法。根据制备诱导性多能干细胞的方法,使用胚胎干细胞衍生的微泡可以有效地进行体细胞的去分化而没有副作用,而且,该方法有望在开发细胞疗法产品中非常有用。具有个人免疫相容性。

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