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METHOD FOR PREVENTING AND TREATING ACUTE RADIATION DISEASE EXPERIMENTALLY

机译：实验性预防和治疗急性放射病的方法

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FIELD: medicine.;SUBSTANCE: melanin having water-solubility of at least 80% and an paramagnetic centre concentration of at least 8·1017 spin/g is administered orally into the animals having been exposed to the radiation in a dose high enough to cause a spinal radiation injury; melanin is administered after dissolved in distilled water in the effective concentration. Melanin water is used as drinking water for the mice having been exposed to single and fractionated acute radiation, which is able to cause acute radiation disease. Melanin water is taken from the 1^st to 30^th day following the single radiation, or from the 1st day of the fractionated radiation to the 30th day on completion of the radiation.;EFFECT: higher survival rate, faster recovered haemopoiesis, body weight and orientation and motion activity.;7 tbl, 5 ex

机译：领域：药物;物质：黑色素具有的水溶性至少为80％，顺磁性中心浓度至少为8·1017 spin / g口服给予动物，剂量足以引起辐射脊柱放射损伤;黑色素以有效浓度溶于蒸馏水中后给药。黑色素水用作已经暴露于单一和分级急性辐射的小鼠的饮用水，这会引起急性辐射疾病。黑色素水取自单次辐射后的第1天至第30天，或取自分次辐射的第一天至辐射完成后的第30天。效果：更高的生存率，更快的造血，体重，定向和运动活动。; 7 tbl，5 ex

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公开/公告号RU2551619C1

专利类型
公开/公告日2015-05-27

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE GOSUDARSTVENNYJ NAUCHNYJ TSENTR ROSSIJSKOJ FEDERATSII-FEDERALNYJ MEDITSINSKIJ BIOFIZICHESKIJ TSENTR IMENI A.I. BURNAZJANA;
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申请/专利号RU20140119837
发明设计人 ABROSIMOVA ALLA NIKOLAEVNA;VOROZHTSOVA SVETLANA VLADIMIROVNA;DOROZHKINA OLGA VASILEVNA;STAVRAKOVA NINA MIKHAJLOVNA;BUSHMANOV ANDREJ JUREVICH;BULYNINA TAISIJA MIKHAJLOVNA;KOTENKO KONSTANTIN VALENTINOVICH;ANDRIANOVA IRINA EFIMOVNA;IVANOV ALEKSANDR ALEKSANDROVICH;SEVERJUKHIN JURIJ SERGEEVICH;
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申请日2014-05-19
分类号G09B23/28;A61K38/02;A61P17/18;A61P39/06;
国家 RU
入库时间 2022-08-21 14:56:21

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