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Broad spectrum vaccine against non-typhoidal Salmonella

机译：抗非伤寒沙门氏菌的广谱疫苗

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摘要

The present invention is drawn to attenuated Salmonella serovar strains S. Typhimurium and S. Enteritidis, conjugate vaccines derived from these attenuated strains of S. Typhimurium and S. Enteritidis, comprising an O polysaccharide covalently linked to a flagellin protein, and methods for inducing an immune response in a subject comprising administering the attenuated strains and/or the conjugate vaccines of the invention.

机译：本发明涉及减毒的沙门氏菌血清型菌株 S。鼠伤寒和 S。肠炎，源自这些减毒的 S菌株的结合疫苗。鼠伤寒和 S。肠溶菌，其包含与鞭毛蛋白共价连接的O多糖，以及在受试者中诱导免疫应答的方法，其包括施用本发明的减毒株和/或缀合物疫苗。 展开▼

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公开/公告号US9050283B2

专利类型

公开/公告日2015-06-09

原文格式PDF

申请/专利权人 MYRON M. LEVINE;RAPHAEL SIMON;JAMES GALEN;SHARON TENNANT;
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申请/专利号US201013144336

发明设计人 MYRON M. LEVINE;RAPHAEL SIMON;JAMES GALEN;SHARON TENNANT;
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申请日2010-01-16

分类号A61K39/112;A61K39;A61K39/385;A61K45;A61K47;

国家 US

入库时间 2022-08-21 15:17:50

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