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MULTIPLE BIOMARKER SET FOR BREAST CANCER DIAGNOSIS, METHOD OF DETECTING THE SAME, AND DIAGNOSIS KIT FOR BREAST CANCER USING ANTIBODY AGAINST THE SAME
MULTIPLE BIOMARKER SET FOR BREAST CANCER DIAGNOSIS, METHOD OF DETECTING THE SAME, AND DIAGNOSIS KIT FOR BREAST CANCER USING ANTIBODY AGAINST THE SAME
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机译:用于乳腺癌诊断的多种生物标志物,检测方法以及使用针对抗体的抗体诊断乳腺癌的试剂盒
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摘要
The present invention relates to a biomarker set for diagnosing breast cancer comprising two or more protein markers of: apolipoprotein C1, apolipoprotein (a), neural cell adhesion molecule L1-like protein, carbonic anhydrase 1, and fibronectin; a method for detecting the biomarker set in a blood sample through a multiple reaction monitoring; a kit for diagnosing breast cancer comprising antibodies specific to each of the proteins of the biomarker set; and a method for detecting proteins of the marker set in a blood sample through an antigen-antibody binding reaction. The method for detecting the protein marker set in a blood sample by the MRM method or antigen-antibody binding reaction and the diagnostic kit can provide very high accuracy and sensitivity in comparison with the diagnosis method using a single marker and can very conveniently diagnose breast cancer using blood from patients, thereby being effectively used for early diagnosis of breast cancer.
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