首页> 外国专利> METHOD TO PREDICT THE PRESENCE OF INFLAMMATION OR ITACONIC ACID, IRG1 AND/OR PROTEIN IRG1 IN A SUBJECT AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING INFLAMMATION

METHOD TO PREDICT THE PRESENCE OF INFLAMMATION OR ITACONIC ACID, IRG1 AND/OR PROTEIN IRG1 IN A SUBJECT AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING INFLAMMATION

机译:预测对象或药物成分中治疗或预防炎症的炎症或衣康酸,IRG1和/或蛋白IRG1的存在的方法

摘要

The present invention is directed to in vitro methods to predict the presence of inflammation, gene IRG1 or protein encoded by IRG1 in a subject by determining presence of itaconic acid in a biological sample isolated from the subject. The invention is also directed to methods to predict the ability of a subject to produce itaconic acid under inflammation by determining the presence IRG1 in a biological sample. The invention is also related to pharmaceutical composition to initiate production of itaconic acid in a subject for preventing or treating inflammation, or bacterial infection.
机译:本发明涉及通过确定从受试者分离的生物样品中衣康酸的存在来预测受试者中炎症,IRG1基因或IRG1编码的蛋白质的存在的体外方法。本发明还涉及通过确定生物样品中IRG1的存在来预测受试者在炎症下产生衣康酸的能力的方法。本发明还涉及用于在受试者中引发衣康酸产生以预防或治疗炎症或细菌感染的药物组合物。

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