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SCREENING METHOD FOR amp;bgr;-ADRENERGIC-LIKE OCTOPAMINE RECEPTOR ACTION SUBSTANCE

机译:类似于肾上腺素的章鱼受体作用物质的筛选方法

摘要

PROBLEM TO BE SOLVED: To provide an easy and efficient screening method for &bgr;-adrenergic-like octopamine RECEPTOR action substance, and a cell for use in the screening method.SOLUTION: This invention relates to use of a cell to which (a) polynucleotide encoding &bgr;-adrenergic-like octopamine receptor protein is introduced and (b) polynucleotide encoding cAMP binding domain fusion type reporter protein in which reporter activity rises by cAMP binding is also introduced.
机译:解决的问题:提供一种用于肾上腺素样章鱼胺受体活性物质的简便有效的筛选方法,以及用于该筛选方法的细胞。解决方案:本发明涉及(a)的细胞的用途。引入编码β-肾上腺素样章鱼胺受体蛋白的多核苷酸,并且(b)还引入编码cAMP结合域融合型报告蛋白的多核苷酸,其中报告子活性通过cAMP结合而增加。

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