METHOD OF TREATING OLD INJURIES OF TENDONS

• 1. 一种治疗老烂腿、老烂脚的中药药膏及其制备方法 [P] . 中国专利： CN105943776A . 2016-09-21
• 2. 可辅助康复髋伤的适老座椅 [P] . 中国专利： CN214596416U . 2021-11-05
• 3. THERAPEUTIC AGENT FOR TENDON AND LIGAMENT INJURY, AND PHARMACEUTICAL COMPOSITION FOR TREATING TENDON AND LIGAMENT INJURY [P] . 日本专利： JP2015205872A . 2015-11-19

  机译： 肌腱和韧带损伤的治疗剂，以及治疗肌腱和韧带损伤的药物组合物

• 4. Bandage for treating injuries to the Achilles tendon, made of elastic material and including a cushion to protect the tendon and an elastic insert at the front to facilitate application [P] . 德国专利： DE202004013159U1 . 2006-01-05

  机译： 用于治疗跟腱损伤的绷带，由弹性材料制成，并包括保护肌腱的垫子和位于前部的弹性插入物，以便于应用

• 5. platelet-derived growth factor compositions and methods for treating tendon and ligament injuries [P] . BRPI0918611A2 . 2019-09-03

  机译： 血小板衍生的生长因子组合物和肌腱和韧带损伤的治疗方法

• 1. Introducing an Innovative Method to Treat Spastic Cerebral Palsy with Faster Recovery Time: Post-Achilles Tendon Lengthening with Bandaging [J] . Hamed Yazdanshenas, Firoozeh Madadi, Kevin Perez, 生物科学与医学（英文） . 2021,第012期
• 2. EIGHTY CASES of SOFT TISSUE INJURY TREATED WITH LOCAL CONTRALATERAL NEEDLING METHOD [J] . 世界针灸杂志：英文版 . 1995,第001期
• 3. Transplantation of tendon-derived stem cells pre-treated with connective tissue growth factor and ascorbic acid in vitro promoted better tendon repair in a patellar tendon window injury rat model [J] . Lui Pauline Po Yee, Wong On Tik, Lee Yuk Wa Cytotherapy . 2016,第1期
• 4. A 2-free-end flexor carpi radialis tendon graft for treating a complex index finger extensor tendon injury [J] . Giovanni Battista Colasanti, Carlotta Pari, Agnese Puzzo, Acta bio-medica: Atenei Parmensis . 2020,第suppla4期
• 5. Identifying, Treating And Rehabbing Soft Tissue Injuries: Getting performance horses back on track after ligament and tendon injuries [J] . Jeff Cota American Farriers Journal . 2015,第2期
• 6. INJURY DURING EARLY NEONATAL DEVELOPMENT LEADS TO A FASTER REPAIR RESPONSE WHEN COMPARED TO LATER INJURY IN A MOUSE ACHILLES TENDON [C] . Ansorge HL, rnHsu JE, rnEdelstein L, ASME summer bioengineering conference;SBC2010 . 2010
• 7. Aging of muscle-tendon units influences common orthopaedic injuries and tendon-to-bone healing. [D] . Plate, Frank Johannes. 2014
• 8. A 2-free-end flexor carpi radialis tendon graft for treating a complex index finger extensor tendon injury [O] . Giovanni Battista Colasanti, Carlotta Pari, Agnese Puzzo, 2020
• 9. The Challenges of Treating Female Soccer Players With ACL Injuries: Hamstring Versus Bone–Patellar Tendon–Bone Autograft [O] . Elise Britt, Ryan Ouillette, Eric Edmonds, 2020

• 1. CLINICAL OBSERVATIONS IN 185 CASES OF LIGAMENT AND TENDON INJURIES TREATED BY THE METHOD OF DISSIPATING BLOOD STASIS AND PROMOTING THE MERIDIAN [J] . 罗庆道 ,邢真美 ,肖伟 . 中医杂志：英文版 . 1989,第1期
• 2. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 3. Successful Painful Treatment of the Painful Achilles Was the Start for Research Providing New Knowledge about Tendon Pain and New Treatment Methods [J] . Hakan Alfredson . 疼痛研究与治疗（英文） . 2014,第2期
• 4. 利用残留伸肌腱治疗伸肌腱撕脱伤一期重建伸拇伸指功能 [C] . 孙玉福 ,王炳祺 ,胡茂忠 . 第二十届全国中西医结合骨伤科学术研讨会、第二届中国医师协会中西医结合医师分会骨伤科学术年会、第十九届浙江省中西医结合骨伤科专业委员会学术年会 . 2013
• 5. 节伤汤内服及节伤散外洗治疗踝关节急性扭急伤性的扭临伤床研究 [A] . 张晓辉 . 2009