首页> 外国专利> Centrifugal microfluidic device for target protein detection and microfluidic system comprising the same

Centrifugal microfluidic device for target protein detection and microfluidic system comprising the same

机译:用于靶蛋白检测的离心微流控装置以及包括该离心微流控装置的微流控系统

摘要

The microfluidic system including the microfluidic device for a centrifugal force based on the target protein, and detecting the same are disclosed. Microfluidic device for the target protein of the centrifugal force-based according to the present invention is detected, the rotating body; The rotor is arranged on the whole, are arranged in a plurality of passages and the passage that connects a plurality of chambers and the plurality of chambers using the centrifugal force according to the comprises a number of valves which control the flow of fluid, and the rotation of the rotor a microfluidic structure for conveying the fluid; Beads having a capture probe (capture probe) having been provided in the microfluidic structure, and the target protein specific affinity to the surface; And being provided in the microfluidic structure, wherein the target has a protein with specific affinity, a detection probe (detection probe) comprises a material required for the optical signal expression, and wherein the microfluidic structure and the bead a biological sample, and characterized in that said detecting and reacting a mixture of probes, washed and remove the bead finish the reaction. ; Microfluidic devices, centrifugal force, the bead, the target protein is detected
机译:公开了包括基于靶蛋白质的用于离心力的微流体装置并对其进行检测的微流体系统。根据本发明的基于离心力的目标蛋白质的微流体装置是检测,旋转体;转子整体上布置,并且布置在多个通道中,并且根据离心力,利用离心力连接多个腔室和多个腔室的通道包括控制流体流动的多个阀,并且转子的旋转为用于输送流体的微流体结构;具有在微流体结构中提供的捕获探针(捕获探针)的珠,并且靶蛋白对表面具有特异性亲和力;并且被提供在微流体结构中,其中靶标具有特异性亲和力的蛋白质,检测探针(检测探针)包含光信号表达所需的材料,并且其中微流体结构和珠子是生物样品,并且其特征在于所述检测探针混合物并使其反应,洗涤并除去珠子完成了反应。 ;微流控设备,离心力,微珠,目标蛋白被检测

著录项

  • 公开/公告号KR101343034B1

    专利类型

  • 公开/公告日2013-12-18

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20070003401

  • 发明设计人 조윤경;이정건;이범석;박종면;

    申请日2007-01-11

  • 分类号G01N33/68;G01N33/53;G01N33/48;G01N35/00;

  • 国家 KR

  • 入库时间 2022-08-21 15:43:59

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