首页> 外国专利> Polyethylene glycol conjugated factor VIIa; Pharmaceutical composition comprising Said polyethylene glycol conjugated factor VIIa; use of a Pharmaceutical composition for treating disease or trauma of Blood coagulation in a patient who needs to prepare the next process; pol Ietilenglicol conjugated to factor VIIa.

Polyethylene glycol conjugated factor VIIa; Pharmaceutical composition comprising Said polyethylene glycol conjugated factor VIIa; use of a Pharmaceutical composition for treating disease or trauma of Blood coagulation in a patient who needs to prepare the next process; pol Ietilenglicol conjugated to factor VIIa.

机译：聚乙二醇共轭因子VIIa;包含所述聚乙二醇共轭因子VIIa的药物组合物;药物组合物在需要准备下一过程的患者中用于治疗凝血疾病或创伤的用途; pol Ietilenglicol与VIIa因子缀合。

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摘要

The present invention provides a biocompatible polymer conjugated to FVIIa via one or more cysteine residues, suitably via a linker across a reduced disulphide bond in FVIIa, and pharmaceutical compositions comprising such conjugated forms of FVIIa.

机译：本发明提供了通过一个或多个半胱氨酸残基，适当地通过跨越FVIIa中还原的二硫键的接头与FVIIa缀合的生物相容性聚合物，以及包含这种缀合形式的FVIIa的药物组合物。

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公开/公告号CL2012003038A1

专利类型
公开/公告日2014-01-24

原文格式PDF
申请/专利权人 CANTAB BIOPHARMACEUTICALS PATENTS LIMITED;POLYTHERICS LIMITED;
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申请/专利号CL20120003038
发明设计人 HENRY WILLIAM;
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申请日2012-10-29
分类号A61K38/36;A61K47/48;
国家 CL
入库时间 2022-08-21 15:58:27

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