a) isolating human spermatogonial stem cells (SSCs), and optionally purifying the same; andb) co-culturing the isolated and optionally purified SSCs with a suitably adjusted Sertoli cell environment to obtain haploid germ cells."/> Human multipotent germ line stem cells expressing a germ line marker and a pluripotency marker produced by co-culture of testicular tissue
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Human multipotent germ line stem cells expressing a germ line marker and a pluripotency marker produced by co-culture of testicular tissue

机译:人多能生殖系干细胞表达通过睾丸组织共培养产生的生殖系标记和多能性标记

摘要

A method of in vitro maturation of adult human germ line cells in an artificial biological environment, which entails:a) isolating human spermatogonial stem cells (SSCs), and optionally purifying the same; andb) co-culturing the isolated and optionally purified SSCs with a suitably adjusted Sertoli cell environment to obtain haploid germ cells.
机译:在人工生物环境中成年人类生殖细胞的体外成熟方法,包括: a)分离人精原干细胞(SSC),并可选地对其进行纯化;和 b)将分离并可选纯化的SSC与适当调节的Sertoli细胞环境共同培养以获得单倍体生殖细胞。

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