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Generating Attenuation Correction Maps for Combined Modality Imaging Studies and Improving Generated Attenuation Correction Maps Using MLAA and DCC Algorithms

机译:生成用于组合模态成像研究的衰减校正图,并使用MLAA和DCC算法改进生成的衰减校正图

摘要

The DCC (Data Consistency Condition) algorithm is used in combination with MLAA (Maximum Likelihood reconstruction of Attenuation and Activity) to generate extended attenuation correction maps for nuclear medicine imaging studies. MLAA and DCC are complementary algorithms that can be used to determine the accuracy of the mu-map based on PET data. MLAA helps to estimate the mu-values based on the biodistribution of the tracer while DCC checks if the consistency conditions are met for a given mu-map. These methods are combined to get a better estimation of the mu-values. In gated MR/PET cardiac studies, the PET data is framed into multiple gates and a series of MR based mu-maps corresponding to each gate is generated. The PET data from all gates is combined. Once the extended mu-map is generated the central region is replaced with the MR based mu-map corresponding to that particular gate. On the other hand, in dynamic PET studies the uptake in the patient's arms reaches a steady state only after the tracer distributes throughout the body. Hence, for dynamic scans, the projection data of all frames is summed and used to generate the MLAA based extended mu-map for all frames.
机译:DCC(数据一致性条件)算法与MLAA(衰减和活动的最大似然重建)结合使用,以生成用于核医学成像研究的扩展衰减校正图。 MLAA和DCC是互补算法,可用于基于PET数据确定mu-map的准确性。 MLAA有助于根据示踪剂的生物分布来估算mu值,而DCC会检查给定mu-map是否满足一致性条件。将这些方法结合起来可以更好地估计mu值。在门控MR / PET心脏研究中,将PET数据分为多个门,并生成与每个门相对应的一系列基于MR的mu-map。来自所有门的PET数据被合并。一旦生成了扩展的mu-map,就将中心区域替换为与该特定门相对应的基于MR的mu-map。另一方面,在动态PET研究中,只有在示踪剂分布到全身后,患者手臂的摄取才会达到稳定状态。因此,对于动态扫描,将所有帧的投影数据相加并用于为所有帧生成基于MLAA的扩展mu-map。

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