首页>
外国专利>
Production method of ceramide in transformed cells with a endoplasmic reticulum localization signal with sphingolipid Δ4- desaturase
Production method of ceramide in transformed cells with a endoplasmic reticulum localization signal with sphingolipid Δ4- desaturase
展开▼
机译：具有鞘脂Δ4-去饱和酶的内质网定位信号的转化细胞中神经酰胺的生产方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides a method for producing human ceramide in cells such as yeast cells. The method of the present invention comprises: 1) introducing, by transformation of the yeast cell, an endoplasmic reticulum localization signal-attached sphingolipid ”4-desaturase gene (DES1m) in which a nucleotide sequence encoding a yeast endoplasmic reticulum localization signal is added to the 3'-end of the sphingolipid ”4-desaturase gene (DES1); and 2) abolishing, by transformation of the yeast cell, the expression of the yeast sphinganine C4-hydroxylase gene (SUR2).
展开▼
