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Including the fact that the human framework is chosen on the basis of
Including the fact that the human framework is chosen on the basis of
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机译：包括以下事实：选择人为框架的依据是
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摘要
PROBLEM TO BE SOLVED: To provide methods for selecting human variable region frameworks for use in human adaptation of non-human monoclonal antibodies such as rodent antibodies.;SOLUTION: The method for selecting human antibody sequences for use in making human-adapted antibody molecules and method for selecting human antibody sequences containing somatic mutations, in particular, the methods select candidate human antibody framework sequences from a database of human germline genes or human sequences with somatic mutations.;COPYRIGHT: (C)2009,JPO&INPIT
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