首页> 外国专利> METHOD FOR ASSESSING CONDITION OF POPULATION OF CELLS, METHOD FOR ASSESSING CARCINOGENICITY OF CANDIDATE COMPOUND AND METHOD FOR ASSESSING ANTI CANCER ACTIVITY OF LATENT ANTICANCER COMPOUND, AND METHOD FOR ASSESSING QUALITY OF THERAPEUTIC CELL POPULATION

METHOD FOR ASSESSING CONDITION OF POPULATION OF CELLS, METHOD FOR ASSESSING CARCINOGENICITY OF CANDIDATE COMPOUND AND METHOD FOR ASSESSING ANTI CANCER ACTIVITY OF LATENT ANTICANCER COMPOUND, AND METHOD FOR ASSESSING QUALITY OF THERAPEUTIC CELL POPULATION

机译：评估细胞种群状况的方法，评估扁桃体化合物致癌性的方法和评估抗癌化合物抗癌活性的方法以及评估治疗性细胞群体的质量的方法

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摘要

PROBLEM TO BE SOLVED: To provide live a cell imaging technology without using fluorescence that is required in assessing quality of mammalian cells, assessing carcinogenicity of compounds, especially in research of carcinogenic substance in low dose or carrying capacity, assessing of compounds, screening of compounds, quality control of cells and/or assessment or the like, and relating to biomarker, to respond these requirements.SOLUTION: Provided are methods for assessing conditions of cell populations comprising culturing mammalian cell populations, tracing individual cells in the cell population, and correlating the frequency and the conditions of cell populations, wherein the frequency is an indicator of the presence or absence of phenotypical and/or genotypical alterations in a cell populations.

机译：解决的问题：提供活细胞成像技术而无需使用荧光，这在评估哺乳动物细胞的质量，评估化合物的致癌性，特别是在低剂量或低载量致癌物质的研究，化合物的评估，化合物的筛选中是必需的解决这些要求的方法，细胞质量控制和/或评估等，以及与生物标志物有关的解决方案：提供了评估细胞群体状况的方法，包括培养哺乳动物细胞群体，追踪细胞群体中的单个细胞并进行关联细胞群体的频率和条件，其中该频率是细胞群体中表型和/或基因型改变是否存在的指示。

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公开/公告号JP2013230145A

专利类型
公开/公告日2013-11-14

原文格式PDF
申请/专利权人 SATO MASAHIKO;SATO SACHIKO;
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申请/专利号JP20130087987
发明设计人 SATO MASAHIKO;SATO SACHIKO;
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申请日2013-04-19
分类号C12Q1/02;G01N33/50;G01N33/15;C12N1;C12N5/071;
国家 JP
入库时间 2022-08-21 16:17:27

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