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VACCINE AGAINST INFLUENZA H5N1 VIRUSES, MEDICAMENT AND TREATMENT OF H5N1 VIRAL INFECTIONS
VACCINE AGAINST INFLUENZA H5N1 VIRUSES, MEDICAMENT AND TREATMENT OF H5N1 VIRAL INFECTIONS
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机译：预防H5N1流感病毒的疫苗，H5N1病毒感染的药物和治疗
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摘要
The invention relates to an antigenic determinant (H5 epitope) of influenza hemagglutinin (H5N1 ) which is conserved over distant H5N1 lineages but not found in related hemagglutinins H1, H2 or H6; antibodies, antibody fragments and receptors against said conserved antigenic determinant of HA which have influenza A neutralizing activity as well as H5N1 specific vaccines on basis of said antigenic determinant. Methods for passive and active vaccinations are also disclosed, i.e. by administering a vaccine having said conserved H5 epitope as antigenic determinant or by administering an effective amount of antibodies against said antigenic determinant.
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