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Combined gene therapy for the treatment of macroscopic gliomas

机译：联合基因疗法治疗宏观神经胶质瘤

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摘要

The present invention relates to vectors expressing Flt3L and TK for use, as a combination therapy, in the treatment of cancer in a mammal that also receives a therapeutically effective quantity of an orally administered nucleoside analogue. The cancer may be a cancer of the brain. The invention also concerns kits comprising such vectors that may be used for treating cancer in mammals.

机译：本发明涉及表达Flt3L和TK的载体，其作为组合疗法用于治疗哺乳动物中的癌症，该哺乳动物还接受治疗有效量的口服核苷类似物。癌症可以是脑癌。本发明也涉及包含可用于治疗哺乳动物癌症的载体的试剂盒。

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公开/公告号EP2338524B1

专利类型
公开/公告日2013-05-22

原文格式PDF
申请/专利权人 CEDARS-SINAI MEDICAL CENTER;
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申请/专利号EP20110153885
发明设计人 LOWENSTEIN PEDRO;CASTRO MARIA;
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申请日2005-08-12
分类号A61K48;A01K67;A61K38/45;A61K38/19;A61P35;A61K31/522;A61K45/06;
国家 EP
入库时间 2022-08-21 16:33:29

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