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DETECTING DNA MISMATCH REPAIR-DEFICIENT COLORECTAL CANCERS
DETECTING DNA MISMATCH REPAIR-DEFICIENT COLORECTAL CANCERS
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机译:检测DNA不匹配缺陷的结肠直肠癌
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摘要
Use of a CAT25 mononucleotide marker in a novel tetraplex PCR for the detection of MSH6-defective colorectal cancers (CRCs) is described herein. The tetraplex PCR of the present invention offers a facile, robust, less expensive (compared to the original pentaplex assay), highly sensitive, and specific assay for the identification of micros atellite instability (MSI) in CRCs.
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