首页> 外国专利> CARNIVORE CUTANEOUS CANDIDIASIS ASSOCIATED VACCINE, METHOD FOR PREPARING CARNIVORE CUTANEOUS CANDIDIASIS ASSOCIATED VACCINE, METHOD FOR PREVENTING AND TREATING CARNIVORE CUTANEOUS CANDIDIASIS

CARNIVORE CUTANEOUS CANDIDIASIS ASSOCIATED VACCINE, METHOD FOR PREPARING CARNIVORE CUTANEOUS CANDIDIASIS ASSOCIATED VACCINE, METHOD FOR PREVENTING AND TREATING CARNIVORE CUTANEOUS CANDIDIASIS

机译:食肉性念珠菌相关疫苗,食肉性念珠菌相关疫苗的制备,预防和治疗食肉性念珠菌的方法

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention refers to veterinary mycology, and concerns preparing a carnivore cutaneous candidiasis vaccine. As antigens the offered associated carnivore cutaneous candidiasis vaccine contains blastospores of immune strains C. albicans No.95 and C. tropicalis No.87 taken in equal proportions (1:1) with a final amount of 10-40 mil. blastospores per 1 cm3 of 0.8-1% sodium thiosulphate. A method for making such vaccine involves separate homogenisation of a biomass of mycotic blastospores in the sodium thiosulphate solution, measurement of the blastospore content, standartisation of the homogenates to the concentration of 10-40 min. blastospores in 1 cm3 by sparing sterilisation by intermittent steaming and mixing of the prepared homogenates. A method for preventing and treating of carnivore cutaneous candidiasis consists in intramuscular introduction of the vaccine at first in one point, and then in 12-16 days in the opposite point in therapeutic doses.;EFFECT: invention enables creating a high-level lasting immunity in carnivores.;3 cl, 2 tbl
机译:领域:发明涉及兽医真菌学,并且涉及制备食肉动物皮肤念珠菌病疫苗。作为抗原,提供的相关食肉动物皮肤念珠菌病疫苗含有免疫菌株白色念珠菌95号和热带念珠菌87号的孢子芽孢,等比例(1:1),最终量为10-40百万。每1 cm 3 的0.8-1%硫代硫酸钠有芽孢。制备这种疫苗的方法包括将硫代硫酸钠溶液中的真菌性芽孢的生物量分别均质化,测量芽孢的含量,将均质物标准溶液化至10-40分钟的浓度。 1 cm 3 中的孢子孢子通过间歇蒸煮和混合制备的匀浆进行少量灭菌。一种预防和治疗肉食性皮肤念珠菌病的方法,在于首先在一个点肌肉注射疫苗,然后在相反剂量的12-16天肌肉注射治疗剂量。食肉动物; 3 cl,2汤匙

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