首页> 外国专利> VACCINE 'BIONOR' AGAINST PLAGUE, VIRAL ENTERITIS, BOTULISM AND PSEUDOMONOSIS IN MINKS, PLAGUE VIRUS VACCINE STRAIN ЭПММ IN CARNIVORE ANIMALS AND PARVOVIRUS VACCINE STRAIN 'GERKULES' IN CARNIVORE ANIMALS

VACCINE 'BIONOR' AGAINST PLAGUE, VIRAL ENTERITIS, BOTULISM AND PSEUDOMONOSIS IN MINKS, PLAGUE VIRUS VACCINE STRAIN ЭПММ IN CARNIVORE ANIMALS AND PARVOVIRUS VACCINE STRAIN 'GERKULES' IN CARNIVORE ANIMALS

机译:疫苗,水生动物,小肠病毒和小肠病毒疫苗

摘要

FIELD: veterinary science, microbiology. SUBSTANCE: invention relates to agents used for specific prophylaxis of diseases in minks, in part, vaccine "Bionor" against plague, viral enteritis, botulism and pseudomonosis. Mixed vaccine "Bionor" has (per a single vaccine dose 1 ml) dried virus-containing liquid of plague virus strain ЭПММ in carnivore animals and stabilizing agent, titer is 102,2 TCD, not less, suspension of adsorbed inactivated culture of parvovirus strain "Gerkules" in carnivore animals, titer is 6log2 RHA, not less, (before inactivation), botulinic adsorbed anatoxin C from the strain Cl. botulinum N 59 5-10 EC and mixed adsorbed suspension of Ps. aeruginosa of strains 381-P-06 N 40, 1677-08 N 63 and "Dn"-05 N 77 taken in the equal amount, 0.9 billion cells. Use of new strains ЭПММ and "Gerkules" as components of vaccine and technology of preparing provides high immunogenicity and thermal stability of mixed vaccine during prolonged storage. EFFECT: enhanced effectiveness of vaccine. 3 cl, 1 ex
机译:领域:兽医学,微生物学。物质本发明涉及用于特异性预防貂皮中疾病的试剂,部分是针对鼠疫,病毒性肠炎,肉毒杆菌中毒和假单胞菌病的疫苗“ Bionor”。混合疫苗“ Bionor”在肉食动物和稳定剂中具有(每剂1毫升单剂量)干燥的鼠疫病毒virusПММ含病毒干燥液和稳定剂,滴度为10 2,2 TCD,不少于细小病毒“ Gerkules”菌株在食肉动物中的灭活吸附培养物的悬浮液,滴度为6log 2 RHA,不少于(灭活前)C1菌株肉毒吸附的毒素C。肉毒杆菌N 59 5-10 EC和Ps的混合吸附悬浮液。以等量的9亿个细胞摄入了菌株381-P-06 N 40、1677-08 N 63和“ Dn” -05 N 77的铜绿假单胞菌。使用新菌株ЭПММ和“ Gerkules”作为疫苗的成分和制备技术可在长期存放期间为混合疫苗提供高免疫原性和热稳定性。效果:提高疫苗效力。 3 cl,1 ex

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