首页> 外国专利> COMPOSITION CONTAINING BRANDISIA HANCEI HOOK. F. EXTRACT OR FRACTION THEREOF FOR PREVENTING AND TREATING DIABETES COMPLICATION

COMPOSITION CONTAINING BRANDISIA HANCEI HOOK. F. EXTRACT OR FRACTION THEREOF FOR PREVENTING AND TREATING DIABETES COMPLICATION

机译：包含洋紫苏洋甘菊钩的成分。 F.为预防和治疗糖尿病并发症而进行的提取或提取

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PURPOSE: A composition containing Brandisia hancei Hook. f. extract or fraction thereof is provided to suppress aldose reductaase activity and to prevent and treat diabetes complication.;CONSTITUTION: A pharmaceutical composition for preventing and treating diabetes complication contains Brandisia hancei Hook. f. extract as an active ingredient. The extract is prepared from branches, stems, or roots of Brandisia hancei Hook. f. using water, low alcohol of C1-C2, mixture solvent or water soluble alcohol. The pharmaceutical composition for preventing and treating diabetes complication contains a fraction prepared from the extract using organic solvent.;COPYRIGHT KIPO 2012

机译：用途：包含白兰地钩的组合物。 F。提供提取物或其部分以抑制醛糖还原酶活性并预防和治疗糖尿病并发症。;组成：一种用于预防和治疗糖尿病并发症的药物组合物，其包含汉兰氏白兰地。 F。提取物作为有效成分。提取物是从白兰地钩的分支，茎或根中提取的。 F。使用水，C1-C2的低级醇，混合溶剂或水溶性醇。预防和治疗糖尿病并发症的药物组合物包含使用有机溶剂从提取物中制备的馏分。; COPYRIGHT KIPO 2012

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公开/公告号KR20120017009A

专利类型
公开/公告日2012-02-27

原文格式PDF
申请/专利权人 KOREA INSTITUTE OF ORIENTAL MEDICINE;
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申请/专利号KR20110081697
发明设计人 KIM JUNG HYUN;KIM YOUNG SOOK;LEE YUN MI;SHON EUN JIN;JUNG DONG HO;KIM CHAN SIK;KIM JIN SOOK;
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申请日2011-08-17
分类号A61K36/80;A61P3/10;A61P3/00;
国家 KR
入库时间 2022-08-21 17:10:35

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11. 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Vascular304Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipidsTranscriptional control and RNA species - Vascular307MicroRNA-34a role in vascular calcification308Local delivery of a miR-146a inhibitor utilizing a clinically applicable approach attenuates neointima formation after vascular injury309Long noncoding RNA landscape of hypoxic endothelial cells310Specific circulating microRNAs levels associate with hypertension, hyperglycemia and dysfunctional HDL in acute coronary syndrome patientsCytokines and cellular inflammation - Vascular313Phosphodiesterase5A up-regulation in vascular endothelium under pro-inflammatory conditions: a newly disclosed anti-inflammatory activity for the omega-3polyunsaturated aatty acid docosahexaenoic acid314Cardiovascular risk modifying with extra-low dose anticytokine drugs in rhematoid arthritis315Conversion of human M-CSF macrophages into foam cells reduces their proinflammatory responses to classical M1-polarizing activation316Lymphocytic myocarditis coincides with increased plaque inflammation and plaque hemorrhage in coronary arteries, facilitating myocardial infarction317Serum osteoprotegerin level predictsdeclined numerous of circulating endothelial- derived and mononuclear-derived progenitor cells in patients with metabolic syndromeGrowth factors and neurohormones - Vascular320Effect of gastrin-releasing peptide (GRP) on vascular inflammationSignal transduction - Heart323A new synthetic peptide regulates hypertrophy in vitro through means of the inhibition of nfkb324Inducible fibroblast-specific knockout of p38 alpha map kinase is cardioprotective in a mouse model of isoproterenol-induced cardiac hypertrophy325Regulation of beta-adrenoceptor-evoked inotropic responses by inhibitory G protein, adenylyl cyclase isoforms 5 and 6 and phosphodiesterases326Binding to RGS3 and stimulation of M2 muscarinic acetylcholine receptors modulates the substrate specificity of p190RhoGAP in cardiac myocytes327Cardiac regulation of post-translational modifications, parylation and deacetylation in LMNA dilated cardiomyopathy mouse model328Beta-adrenergic regulation of the b56delta/pp2a holoenzyme in cardiac myocytes through b56delta phosphorylation at serine 573Nitric oxide and reactive oxygen species - Vascular331Oxidative stress-induced miR-200c disrupts the regulatory loop among SIRT1, FOXO1 and eNOS332Antioxidant therapy prevents oxidative stress-induced endothelial dysfunction and Enhances Wound Healing333Morphological and biochemical characterization of red blood cell in coronary artery diseaseCytoskeleton and mechanotransduction - Heart336Novel myosin activator, JSH compounds, increased myocardial contractility without chronotropic effect in ratsExtracellular matrix and fibrosis - Vascular339Ablation of Toll-like receptor 9 causes cardiac rupture after myocardial infarction by attenuating proliferation and differentiation of cardiac fibroblasts340Altered vascular remodeling in the mouse hind limb ischemia model in Factor VII activating protease (FSAP) deficiencyVasculogenesis, angiogenesis and arteriogenesis343Pro-angiogenic effects of proly-hydroxylase inhibitors and their potential for use in a novel strategy of therapeutic angiogenesis for coronary total occlusion344Nrf2 drives angiogenesis in transcription-independent manner: new function of the master regulator of oxidative stress response345Angiogenic gene therapy, despite efficient vascular growth, is not able to improve muscle function in normoxic or chronically ischemic rabbit hindlimbs -role of capillary arterialization and shunting346Effect of PAR-1 inhibition on collateral vessel growth in the murine hind limb model347Quaking is a key regulator of endothelial cell differentiation, neovascularization and angiogenesis348"Emerging angiogenesis" in the chick chorioallantoic membrane (CAM). 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