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Methods and means for determining a functional polymorphism in ficolin-2 for predicting the outcome of kidney transplantation

机译:确定ficolin-2功能多态性以预测肾移植结果的方法和手段

摘要

The present invention provides a method for prediction of renal transplantation outcome, for assessment of the risk of post-transplantation kidney rejection, and/or for selecting an appropriate treatment, therapeutic agent or therapeutic agent dosage regime for the treatment of post-transplantation kidney rejection, whereby the presence and/or absence of at least one nucleic acid polymorphism in the gene for ficolin-2 of the kidney is detected. Further provided are oligonucleotides and kits for use in such method.
机译:本发明提供了用于预测肾移植结果,评估移植后肾排斥的风险和/或选择适当的治疗,治疗剂或治疗剂剂量方案的方法,用于治疗移植后肾排斥。 ,由此检测到肾脏的Ficolin-2基因中是否存在至少一种核酸多态性。还提供了用于这种方法的寡核苷酸和试剂盒。

著录项

  • 公开/公告号EP2508618A1

    专利类型

  • 公开/公告日2012-10-10

    原文格式PDF

  • 申请/专利权人 INNOGENETICS N.V.;

    申请/专利号EP20110160949

  • 发明设计人 CLAAS FRANS;DE CANCK ILSE;EIKMANS MICHAEL;

    申请日2011-04-04

  • 分类号C12Q1/68;

  • 国家 EP

  • 入库时间 2022-08-21 17:11:36

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